Certainly not for the first time since the Falklands. In the 2006 Lebanon War when Hezbollah fired two C802 missiles at Israeli warships, and one hit the corvette INS Hanit.If Indeed the Moskva has been hit by missiles (Ukrainian Neptunes or otherwise) it means that we have the first engagement of a major surface combatant with AShM since the Falklands.
The lesson based on the results of a very few actual precedents, is that the Missile invariably gets through.
A sobering thought for all Navies but especially for those that typically operate very far from their home shores.
In 2016, the USS Mason (DDG-87) reported coming under attack in the Red Sea by cruise missiles fired from Houthi group, analysis of the damage caused by that missile led experts to believe it was a Iranian Noor (C-802 Iran version).