Coronavirus 2019-2020 thread (no unsubstantiated rumours!)

Intrepid

Major
Washington (CNN) Republican Sen. Richard Burr of North Carolina is stepping aside as chairman of the influential Senate Intelligence Committee while he's under investigation for stock trades he made ahead of the market downturn sparked by the coronavirus pandemic.

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Hendrik_2000

Lieutenant General
Here is the original article that you are talking about.

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And below is their description of the type A strain:

“There are two subclusters of A which are distinguished by the synonymous mutation T29095C. In the T-allele subcluster, four Chinese individuals (from the southern coastal Chinese province of Guangdong) carry the ancestral genome, while three Japanese and two American patients differ from it by a number of mutations. These American patients are reported to have had a history of residence in the presumed source of the outbreak in Wuhan. The C-allele subcluster sports relatively long mutational branches and includes five individuals from Wuhan, two of which are represented in the ancestral node, and eight other East Asians from China and adjacent countries. It is noteworthy that nearly half (15/33) of the types in this subcluster, however, are found outside East Asia, mainly in the United States and Australia.”

Half of the type A strain is still linked to Wuhan. They did point out that nearly half of the subtype with the C-allele mutations are found outside of East Asia. However, they didn’t say the travel and residence history of these patients. These data were obviously collected from patient samples early in the outbreak. Based on the case reports outside of China at the time (early days of the outbreak), most of the countries outside of China only tested people with travel history to China. That would means that these patients outside of East Asia should all have travel history to China.

Secondly, the original parent strain used in their study for comparing all the viral genomes was isolated from a Yunnan local bat species. And the authors of your article also said that the type-A strain evolved from this parent strain found in Yunnan bats. So how do you think a virus, that lives in a bat species local to central China of Yunnan province, managed to jump across half of China and the entire Pacific ocean and infect Americans? And while doing so, not touching a single Chinese in between? Did the Americans sneak into China and steal some Chinese bats and bring them back to the US? Then they infect their own people and went back to China? Uhhhh. How do you plan to prove any of these?

It does not proof that the A type is prevalent in China it only cite 4 Individual from Quangzhou is victim from this strain of virus
only 96% of the corona virus gene is common to gene of corona virus found in yunnan bat. BUT 4% DIFFERENCE TAKE EON TO MUTATE. HUMAN AND CHIMP SHARE 99% OF THE GENE ARE YOU SAYING THAT CHIMP AND HUMAN ARE THE SAME ?


citing your paper here is the conclusion
In a phylogenetic network analysis of 160 complete human severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) genomes, we find three central variants distinguished by amino acid changes, which we have named A, B, and C, with A being the ancestral type according to the bat outgroup coronavirus. The A and C types are found in significant proportions outside East Asia, that is, in Europeans and Americans. In contrast, the B type is the most common type in East Asia, and its ancestral genome appears not to have spread outside East Asia without first mutating into derived B types, pointing to founder effects or immunological or environmental resistance against this type outside Asia. The network faithfully traces routes of infections for documented coronavirus disease 2019 (COVID-19) cases, indicating that phylogenetic networks can likewise be successfully used to help trace undocumented COVID-19 infection sources, which can then be quarantined to prevent recurrent spread of the disease worldwide.
 
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Gatekeeper

Brigadier
Registered Member
Are there any current long term contracts? Anyway that tailings dam collapse in Brazil has restricted Brazil's output I believe it could take another couple of years to regain lost production.

Not sure about current long term contract. And sure the Brazil gambit could back fire on China. But then again given the downturn in economic activities in the past three months and the foreseeable future, it certainly wouldn't pay to be in the primary industrial food chain!
 

Gatekeeper

Brigadier
Registered Member
China should just cut off all medical supplies to the US.

It's best China not do that, otherwise Trump will be stealing supplies from her allies again. Lol. (Sarcasm mode full on)!

The more I look into this, the more I think Trump is such a simpleton. But he has educated people around him to advise him. Do these people only advise him what he wants to hear? I mean the trade war was supposed to be easy to win. Right? How's that going?

And now this great $500 billion give away he keeps harping on about. It must only be for his support base of the uneducated. Lol. USA don't just give this $500 billion away, from the goodness of her heart for nothing. In exchange for this $500 billion (all printed in pieces of paper), China has given away something substantial in return. ie: the iPhone's this uneducated simpleton used to type their hatred of all things Chinese!
 

vesicles

Colonel
It does not proof that the A type is prevalent in China it only cite 4 Individual from Quangzhou is victim from this strain of virus
only 96% of the corona virus gene is common to gene of corona virus found in yunnan bat. BUT 4% DIFFERENCE TAKE EON TO MUTATE. HUMAN AND CHIMP SHARE 99% OF THE GENE ARE YOU SAYING THAT CHIMP AND HUMAN ARE THE SAME ?

They decided to use the genome of the Yunnan bat virus as an outgroup based on the findings of Zhou, et al., which proposes the Yunnan bat as a possible original host of the virus.

citing your paper here is the conclusion
In a phylogenetic network analysis of 160 complete human severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2) genomes, we find three central variants distinguished by amino acid changes, which we have named A, B, and C, with A being the ancestral type according to the bat outgroup coronavirus. The A and C types are found in significant proportions outside East Asia, that is, in Europeans and Americans. In contrast, the B type is the most common type in East Asia, and its ancestral genome appears not to have spread outside East Asia without first mutating into derived B types, pointing to founder effects or immunological or environmental resistance against this type outside Asia. The network faithfully traces routes of infections for documented coronavirus disease 2019 (COVID-19) cases, indicating that phylogenetic networks can likewise be successfully used to help trace undocumented COVID-19 infection sources, which can then be quarantined to prevent recurrent spread of the disease worldwide.

First of all, that's not my paper. It's a paper that you cited to counter my point. I simply found the original paper for you.

Secondly, you simply cited their Abstract. Yes, that's their main findings. However, you are simplifying and at the same time over-interpreting their findings. Yes, they found A and C mainly in Europe and America and B mainly in East Asia. That does not conclude the A started in America. First of all, they also found A in China, just a minor population (as I specified in my earlier post). As they stated in their paper, they don't know why B is predominant in East Asia, while A and C dominate in Europe and America. Their suggestion is that some kind of geographical selection processes, such as a complex founder scenario or type-B somehow became more suitable among East Asians because of some environmental factors. None of their data suggests that type-A originated outside of China. And they have not implied that their data point to such possibility. You cannot over-interpret their data.

I again urge you to look at the most updated phylogenetic map of the transmission routes of the virus.

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I honestly find the "US military personnel" hypothesis as ridiculous as the "Wuhan lab leak" hypothesis. They are both based on similar kinds of weak evidence of some "suspicious activities" by certain individuals and/or organizations. Both unsubstantiated. Both speculative at best. Both require cherry-picking a minor portion of evidence, while filtering out vast majority of solid evidence countering their views.
 
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