I find this very interesting, and perhaps our resident health science experts can help shed some light. Why does the 2019-nCoV seem to affect children less seriously than older adults? It is my understanding that children, along with the elderly, are usually the more vulnerable age groups to flu.
As the nCOV-2019 is still very new, it is probably too early to make any epidemiological speculations. Taking an educated guess with its near cousin SARS, which exhibits very similar genetic sequence and both using ACE2 as the cell receptor, I would quote this passage from the paper below:
The epidemiology of severe acute respiratory syndrome in the 2003 Hong Kong epidemic: an analysis of all 1755 patients.
In addition, the risk for acquiring infection varied significantly by age, with relatively few cases of infection and no deaths in children and adolescents. The reasons for this are unclear. One hypothesis relating to mild or asymptomatic infection in young patients has not been borne out by detailed serologic testing of case contacts (25). Alternative hypotheses, including one that suggests that more recent infections in young patients with other coronaviruses confer some degree of protection to SARS coronavirus due to antigenic cross-reactivity, have not as yet been tested. Current prevailing theories focus on an attenuated immunopathologic response in children because of a more immature immune system (26). However, the exact mechanism that leads to SARS coronavirus–induced immunomodulation remains to be elucidated (27).
Graph of age distribution and SARS cases
![6ff3.png](https://acp.silverchair-cdn.com/acp/content_public/journal/aim/20076/6ff3.png?Expires=1580513159&Signature=4w16yThBTkHgizB4Dc-mDF357mXDFSuXXatPvR~4pswrS5fhRyDbyAR3mO~qg5y1MFXkyhGt5jPZo69ZoSWlD31vs-ofuma4skfmspyMkIm~3L-oP4-Iupw~5BbbQOQjDTy9z2s1nAfDgGGu~Yj-RzHu3MWEHyqAJ2idJ2y24ciPWCZN4VLNEUapaef6B75fEBTqkL3fwHZii~M~6os4t~w3Rc3THKtj8E2~vJ0zc2-qA-BukMJbMgKL7qHrL8EjWdAW8SY7H3O1gWHcbk4mzVLxMdJ7I9YOoGVZRH0ulKeGGFumLKiBUpHhfXoGxA1D5oYLTZcv4VMVyRmhwvM4mg__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)