Ref Point 2. Wouldn't you get the overall hospital admittance rate for serious cases with a large scale sampling of the Wuhan (or Guangdong) population with a blood antibody test? This will give you the overall number of infected. Presumably this is happening very soon, if not already.
3a. Given a very healthy cohort of 18-40 year old subjects with no pre-existing conditions, what sort of timescales are we typically looking at for a full recovery from pneumonia? And is pneumonia the only realistic complication?
3b. Are there any comparable coronaviruses which would give us an indication on whether that healthy 18-40 cohort with mild symptoms would suffer any long-term effects?
Say that healthy 18-40 cohort has been infected by a particular strain of the Coronavirus, how long could we expect immunity to that same strain to last for:
4a. Assuming they weren't exposed again?
4b. Assuming they were to be continually exposed to low levels of the same coronavirus strain?
For 2, sampling a large population in Wuhan of 11 million people wouldbe close to impossible, cost wise and time wise. Recruiting those people for sampling is also impossible.In a typically clinical study, gathering data from 11 million people is physically impossible.
3a, I honestly have no idea. This is a new virus. No one at this point can know what sort of long term effects patients may have. As you can see, this particular Coronavirus has thrown us curve balls after curve balls. We will just have to wait and see.
3b, The closest comparison would be the SARS. What I mentioned before would be based on observations of SARS patients.
4a, as I’ve mentioned before, it all depends on how fast the virus mutates. Typically, we would assume 6 months, based on what we know about influenza. This is all a guess since we only found out about the COVID-19 about 2 months ago. Too little time for us to find out how fast it mutates and how well we can stay immune.
4b, this would be a nightmare that no one wants to experience. Being Continuously exposed to a virus? We are not even allowed to do such a thing to lab mice. Assuming we are not abducted by torturous aliens who want to do terrible experiments on us, no one should expect this kindof thing to happen in the real world.
Sorry to ask, but have you or someone you know contracted the virus? You seem to be focused squarely on a specific group of people...