In the trial of VV116, more than 380 people took the experimental drug, while a similarly sized group took Paxlovid. Both treatment courses lasted five days.
The median time to recovery — defined as no Covid symptoms for two consecutive days —
was four days for VV116 recipients and five days for those who took Paxlovid. After four weeks, around 98% of all participants had recovered, and no one developed severe Covid.
Study co-author Ren Zhao, a professor at Shanghai Jiao Tong University School of Medicine, called the trial a “great success” in
Thursday.
When it comes to specific side effects, around 26% of the trial participants who took Paxlovid said it altered their sense of taste — food tasted sour, sweet, bitter or metallic — but just 4% of people who took VV116 reported that experience. Although some people in both groups had elevated levels of triglycerides (fat in the blood that can increase the risk of heart disease or stroke), a smaller share of those in the VV116 group saw that effect: 11% compared to 21% of participants who took Paxlovid.