Coronavirus 2019-2020 thread (no unsubstantiated rumours!)

[tankphobia]

So what I thought about did come to pass, China is indeed choosing to opening up earlier rather than risk a insane outbreak during Chinese New year's. I wonder how much did those protest influence government policy, they must have some internal metrics for general population sentiment through aggregating social media responses.

I really hope the health system is prepared for what's coming, the next few months will be a real test of whether the extra time brought on by strict policy was enough to increase medical capacity.

 

[Quickie]

I sense a bit of bias on the China department as usual, lol, but he also commented about how inactivated vaccines, like Sinovac, use the entire virus as the antigen. In fact, I recall a Singapore expert who commented about the same points in favor of inactivated vaccines but was kind of shut off and never heard of again.

The doctor also commented about the possible merits of an mRNA vaccine (amazingly there is one such mRNA vaccine in development in China) that uses other parts of the virus other than the spike protein site.

 

[vincent]

I sense a bit of bias on the China department as usual, lol, but he also commented about how inactivated vaccines, like Sinovac, use the entire virus as the antigen. In fact, I recall a Singapore expert who commented about the same points in favor of inactivated vaccines but was kind of shut off and never heard of again.

The doctor also commented about the possible merits of an mRNA vaccine (amazingly there is one such mRNA vaccine in development in China) that uses other parts of the virus other than the spike protein site.

seriously, if you really want to learn more about viruses and vaccines, listen to a real virologist

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[Quickie]

In the US, about 70% got two doses of vaccines. That is why they cannot contain covid. In China, they could have done much better with over 90% vaccinations with mRNA vaccines. All these repeated testing and strange lockdowns is not going to increase anti-bodies. You need more vaccine boosters.

University of Hong Kong has research showing 2 doses of mRNA vaccines are more effective than 3 doses of Sinovac.
Sinovac is still effective, but you need more boosters.

Which University of Hong Kong research is that? AFAIK, there is only one, here. Sinovac is slightly better at preventing death at 3 doses.

 

[Franklin]

China doesn't have to wait for a expensive and "high tech" MRNA vaccine to reopen. A old fashion inactive vaccine based on the Omicron variant is good enough.

You want to develop the MRNA technology for later use but to reopen is not necessary.

PS does anyone know if China has a inactive Omicron vaccine in use ?

 

[henrik]

China doesn't have to wait for a expensive and "high tech" MRNA vaccine to reopen. A old fashion inactive vaccine based on the Omicron variant is good enough.

You want to develop the MRNA technology for later use but to reopen is not necessary.

PS does anyone know if China has a inactive Omicron vaccine in use ?

A Chinese mRNA vaccine has already been approved in Indonesia. This baffles you when they refuse to utilize their own mRNA vaccine.

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[Quan8410]

One of the reason why china can't convince people to get vaccine might be due to Christian belief and them being anti vaxxers. How did Christianity anti vaxx brainrot reached into 105 + iq of Chinese people ?

105+ is average for the whole nation. So there will be a lot of people below that no matter if Christian or not (Some of the best genius in history are Christians including Newton, Euler, Leibniz). Even with people with 200 IQ there must be some people with 50 IQ to make it 105+ assume IQ follows Gaussian distribution. No matter how high the national IQ is, China will have millions of stupid people who are antivaxxing. It is normal everywhere. China should do one thing: VACCINE MANDATE. If China develop vaccine and not forcing everyone to take it, it is meaningless and they will have to resort to lockdown everytime. They even stated that low vaccination is the main reasons for lockdown but they cannot find a way to convince people to take vaccine.

 

[Biscuits]

A Chinese mRNA vaccine has already been approved in Indonesia. This baffles you when they refuse to utilize their own mRNA vaccine.

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Because, generally speaking, the efficiency is lower compared to vaccines that can utilize the whole antigen of the virus compared to just the spike protein, which may constantly change between variants.

In order to be approved in China, a vaccine needs to not just be highly effective but also needs not be heavily dependent on boosters... The public doesn't want to vaccinate 5 times in 1 year.

Possibly MRNA vaccine can work but requires a new approach where much larger parts of the virus are encoded. I'm not sure how this would work, but it could allow them to reach same or even higher efficiency as more difficult attenuated vaccines.

China doesn't have to wait for a expensive and "high tech" MRNA vaccine to reopen. A old fashion inactive vaccine based on the Omicron variant is good enough.

You want to develop the MRNA technology for later use but to reopen is not necessary.

PS does anyone know if China has a inactive Omicron vaccine in use ?

They have this "technology" since a long time and can make as much as they want for export towards states with lower vaccine requirements.

The real technology that everyone wants is a way to isolate disease causing vectors of covid which does not change between different variants, and then a gold standard attenuated/inactivated vaccine can be made which will make the virus near extinct, like polio.

 

[measuredingabens]

Because, generally speaking, the efficiency is lower compared to vaccines that can utilize the whole antigen of the virus compared to just the spike protein, which may constantly change between variants.

In order to be approved in China, a vaccine needs to not just be highly effective but also needs not be heavily dependent on boosters... The public doesn't want to vaccinate 5 times in 1 year.

Possibly MRNA vaccine can work but requires a new approach where much larger parts of the virus are encoded. I'm not sure how this would work, but it could allow them to reach same or even higher efficiency as more difficult attenuated vaccines.


They have this "technology" since a long time and can make as much as they want for export towards states with lower vaccine requirements.

The real technology that everyone wants is a way to isolate disease causing vectors of covid which does not change between different variants, and then a gold standard attenuated/inactivated vaccine can be made which will make the virus near extinct, like polio.

An mRNA vaccine encoding multiple coronavirus epitopes may or may not be more effective given there isn't a single point of failure as is the case with the current ones encoding the spike proteins. I'll need to do quite a bit more reading on the available literature before I can say any more. Nasal vaccines may also be a promising option given that mucosal immunity would offer greater protection due to faster immune response directly at the site of infection, though given their very recent deployment there isn't a whole lot of data on their efficacy in humans.

 

[Han Patriot]

Both Hong Kong and Shanghai did well in the situation. In the case of Shanghai, they didn't even have mRNA vaccines, even though Shanghai Fosun owns the rights in China region for Pfizer vaccines. You should contain covid by vaccine boosters, not by repeated testing.

People are now watching the World Cup in crowded stadiums, with no face masks at all. In China they still limit dining out.

Are you in China? I just had dinner in a friggin hotpot restaurant with no masks on. Lolol. Seriously man.