One of my research focus is a group of drugs first found in tree saps, nonsteroidal anti-inflammatory drugs (NSAIDs). Man, I was trying hard not to get into it since it's kind of hard to get me to shut up once I start talking about it (I'm passionate about what I do
![Big Grin :D :D](data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7)
). Well, you asked for it.
Salicylic acid (the active metabolite in aspirin) was first found in willow saps. And many ancient cultures treated wounds and inflammations with willow tree saps. It was first "officially" found in the 1600's and isolated by Bayers later. Aspirin was synthesized based on salicylic acid in the late 1800's to minimize its serious side effects. Well, we know how widely used these drugs are nowadays. We actually got an Army grant to study the ability of NSAIDs to treat spinal cord injury suffered by soldiers on the battle filed. We are also studying the ability of NSAIDs to prevent/slow down cancer development (clinical studies found that long-term use of NSAIDs can prevent many cancers by as much as 50%. We just don't know how they do it).
My research is actually fighting the mainstream dogma for the molecular mechanism of NSAIDs, which helped developed all the COX-2 inhibitors, like Vioxx and celebrex. We all know how effective they are
![Frown :( :(](data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7)
We are suggesting a completely different mechanism (something to do with cell membranes), which is gaining momentum now, but still not getting accepted by the mainstream. Many biologists choose to ignore what we found because it would most likely invalidate what they have been doing for decades. But if what we found is true, it will revolutionize the way all drugs (not only NSAIDs) are being designed and even the entire biology (like how membrane proteins function and how cell signaling is being conducted).
Well, to answer your question, yes, many trees have medicinal use and we need to explore more :nana: