Coronavirus 2019-2020 thread (no unsubstantiated rumours!)

vesicles

Colonel
An interesting new study from Israel... People have been worried about declining immune responses of the vaccines. An interesting observation of this study is that these COVID vaccines may continue to work for an extended period of time.

Specifically, many patients who have been infected with COVID-19 show declining antibody levels after they recover. This declining antibody level has been worrying a lot of people. When you have no antibody left in your body, how can you fight another future infection? Similarly, if you cannot even maintain a good level of antibody after an actual infection, how can you maintain any effective amount of antibodies after a relatively mild "infection" of vaccination?? This, of course, has been worrisome to many. This new study included 17 subjects who have recovered from a prior actual COVID-19 infection. Before their Pfizer vaccination, they showed almost no antibody against COVID, suggesting that they might be susceptible to another infection. Yet, 21 days after their first Pfizer dose, huge amount of antibodies against COVID have been found in these people. Their anti-COVID antibody levels are 10 times higher than those without a prior COVID infection and just a plain 1 vaccine dose. This findings suggest that, although your antibody levels slowly decline after you recover from an infection, your immune cells still remember the infection well. Upon another potential infection, your immune cells respond quickly to the second infection. This also suggests that vaccine should also work in a similar fashion. So sometime after your vaccination, your antibody level may slowly disappear. But that does not mean you have lost immunity against COVID. IF/when your body sees another batch of COVID virus, your immune cells will respond quickly to deal with the new infection.

Of course, their new study only included 17 subjects with a prior infection. So keep in mind the small sample size.

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B.I.B.

Captain
An interesting new study from Israel... People have been worried about declining immune responses of the vaccines. An interesting observation of this study is that these COVID vaccines may continue to work for an extended period of time.

Specifically, many patients who have been infected with COVID-19 show declining antibody levels after they recover. This declining antibody level has been worrying a lot of people. When you have no antibody left in your body, how can you fight another future infection? Similarly, if you cannot even maintain a good level of antibody after an actual infection, how can you maintain any effective amount of antibodies after a relatively mild "infection" of vaccination?? This, of course, has been worrisome to many. This new study included 17 subjects who have recovered from a prior actual COVID-19 infection. Before their Pfizer vaccination, they showed almost no antibody against COVID, suggesting that they might be susceptible to another infection. Yet, 21 days after their first Pfizer dose, huge amount of antibodies against COVID have been found in these people. Their anti-COVID antibody levels are 10 times higher than those without a prior COVID infection and just a plain 1 vaccine dose. This findings suggest that, although your antibody levels slowly decline after you recover from an infection, your immune cells still remember the infection well. Upon another potential infection, your immune cells respond quickly to the second infection. This also suggests that vaccine should also work in a similar fashion. So sometime after your vaccination, your antibody level may slowly disappear. But that does not mean you have lost immunity against COVID. IF/when your body sees another batch of COVID virus, your immune cells will respond quickly to deal with the new infection.

Of course, their new study only included 17 subjects with a prior infection. So keep in mind the small sample size.

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It would be interesting to see if the immune system responds to the newer variants in the same way.
 

vesicles

Colonel
It would be interesting to see if the immune system responds to the newer variants in the same way.
Yes, I agree. To this day, almost all the data on the new variants are limited to lab work. They show that Pfizer and Moderna vaccines are equally effective against the UK variants, but become significantly less effective (6 times less) against the South African variant. These are all cell culture work. We need real world data, or at least clinical trials. I'm sure people are doing it somewhere. I am almost 100% sure the Israelis are gathering real world data on these as we speak. We just need to be patient...
 

vesicles

Colonel
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China doesn't have to give them shit
I think they should provide such data. When we publish our studies, everything related to these published work must be available to whomever wants to see it. We must sign forms to agree that we must provide detailed information on ALL materials used in our studies. All recipes and ingredients of our reagents (if we make them ourselves), along with company names, catalogue numbers and even batch numbers (along with expiration dates) of all purchased materials, must be provided. When someone contacts us and requests some of our reagents, DNA, proteins, cell lines, animal models, etc, we must provide them openly and freely. Everything and anything related to the published work must be openly available to everyone. This has been the custom. If we all agree that everything should be done scientifically, then they need to adhere to the accepted rules.

At one time, we submitted our manuscript to a journal, a reviewer suggested that we should put all our raw microscopic images on the journal's server. That's over a thousand images that almost no one will ever look at again. Yet, it is our responsibility to openly share all our materials. So we did exactly as the reviewer suggested. It is our duty to do so.
 

B.I.B.

Captain
An interesting new study from Israel... People have been worried about declining immune responses of the vaccines. An interesting observation of this study is that these COVID vaccines may continue to work for an extended period of time.

Specifically, many patients who have been infected with COVID-19 show declining antibody levels after they recover. This declining antibody level has been worrying a lot of people. When you have no antibody left in your body, how can you fight another future infection? Similarly, if you cannot even maintain a good level of antibody after an actual infection, how can you maintain any effective amount of antibodies after a relatively mild "infection" of vaccination?? This, of course, has been worrisome to many. This new study included 17 subjects who have recovered from a prior actual COVID-19 infection. Before their Pfizer vaccination, they showed almost no antibody against COVID, suggesting that they might be susceptible to another infection. Yet, 21 days after their first Pfizer dose, huge amount of antibodies against COVID have been found in these people. Their anti-COVID antibody levels are 10 times higher than those without a prior COVID infection and just a plain 1 vaccine dose. This findings suggest that, although your antibody levels slowly decline after you recover from an infection, your immune cells still remember the infection well. Upon another potential infection, your immune cells respond quickly to the second infection. This also suggests that vaccine should also work in a similar fashion. So sometime after your vaccination, your antibody level may slowly disappear. But that does not mean you have lost immunity against COVID. IF/when your body sees another batch of COVID virus, your immune cells will respond quickly to deal with the new infection.

Of course, their new study only included 17 subjects with a prior infection. So keep in mind the small sample size.

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oops my time ran out to add an after thought



I wonder if different viruses found in bats can absorb characteristics of other types of virus which then result in a super duper virus. Scientists have been going around trying to find the intermediate host for covid the covid virus however, bats are also a carrier of the Lyssavirus which can be found in Australia I think it belongs to the rabies family of viruses, and the thing about them is that they don't require an intermediate host.

However the Flu virus changes so much every seaso we have to get vaccinated every year the same might be said of covid.
 
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vesicles

Colonel
oops my time ran out to add an after thought



I wonder if different viruses found in bats can absorb characteristics of other types of virus which then result in a super duper virus. Scientists have been going around trying to find the intermediate host for covid the covid virus however, bats are also a carrier of the Lyssavirus which can be found in Australia I think it belongs to the rabies family of viruses, and the thing about them is that they don't require an intermediate host.

However the Flu virus changes so much every seaso we have to get vaccinated every year the same might be said of covid.
I believe some viruses do exchange their genetic materials. The recombination seem to be limited to species of the same kind if viruses. Like some coronaviruses exchange their codes... Interesting read below...

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localizer

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