Coronavirus 2019-2020 thread (no unsubstantiated rumours!)

Skye_ZTZ_113

Junior Member
Registered Member
withdrawn as answer already provided
Yeah I misunderstood the news, probably should have looked at any actual accompanying scientific report(s) rather than a news report by itself. Devil is in the details as it's turning out....

Too late to edit so I just left the earlier post behind.
 

Tam

Brigadier
Registered Member
Someone here once asked about whether the mink farm coronavirus cases in Denmark would reduce the finger-pointing at China. One poster here immediately answered on a negative note. He is right. This doctor is already linking the mink farm to China and Hong Kong although he admittedly said it's a hunch as he hasn't bothered to check. His reasoning went along the line that the people in China are less enlightened than the European!

Apparently, the mink farm coronavirus cases have been going on for quite some time. What took them so long to only try to sequence the virus genome only now?


To his defense, this doctor has said publicly he believes in China's numbers and results and sees no reason why not to believe them when the rest of the Western MSM are casting doubt on China's numbers and recovery.
 

Quickie

Colonel
To his defense, this doctor has said publicly he believes in China's numbers and results and sees no reason why not to believe them when the rest of the Western MSM are casting doubt on China's numbers and recovery.

He has to, as it's the case with all the other western naysayers when they see the people in Wuhan were already coming out to party in some big public swimming pools.

You should watch the rest of his videos. You should be able to gather where his stand is, either by direct or indirect inference, on the ability of the Chinese authorities, scientists/doctors in their handling of the virus pandemic.

In one video, he blames the Chinese doctors for claiming that chloroquine could be effective in curing COVID-19.
In another video, he agreed with Trump that COVID-19 could have been leaked from a lab in Wuhan and said that Trump has no reason to lie. And that was during the time when Trump was making the claim that disinfectants should be injected into the body to kill the virus.
 

B.I.B.

Captain
He has to, as it's the case with all the other western naysayers when they see the people in Wuhan were already coming out to party in some big public swimming pools.

You should watch the rest of his videos. You should be able to gather where his stand is, either by direct or indirect inference, on the ability of the Chinese authorities, scientists/doctors in their handling of the virus pandemic.

In one video, he blames the Chinese doctors for claiming that chloroquine could be effective in curing COVID-19.
In another video, he agreed with Trump that COVID-19 could have been leaked from a lab in Wuhan and said that Trump has no reason to lie. And that was during the time when Trump was making the claim that disinfectants should be injected into the body to kill the virus.

He is quiet interesting to listen to, but ruins it with his silly prejudices.
 

Gatekeeper

Brigadier
Registered Member
Donald Trump Jr. has come charging conspiracy because they didn't release this information on Pfizer's vaccine until after the election so Trump can't take credit but then Pfizer has said they didn't get one dime from the government.

It didn't stop Mike Pence trying to take credit on behalf of the orange one though.
 

localizer

Colonel
Registered Member
Are phase 3 trials typically peer reviewed? I am very dubious about this Pfizer trial’s robustness.

The n is still relatively small and like I said it’s only 7 days after the 2nd vaccine dose. Also it needs to be store in -80 or will perish 5 days in fridge.

that said this vaccine has shown the best results yet.

don’l let the market trick you thinking it’s a magic bullet though! The vaccine likely won’t give available thus flu season.
 
Last edited:

vesicles

Colonel
Are phase 3 trials typically peer reviewed? I am very dubious about this Pfizer trial’s robustness.
In order to get formal approval from FDA, they will have to publish their data. That will require peer review.

For effectiveness of vaccines, it is tolerable to have a small scale trial, especially in an urgent time like now. You will need a very large n (typically thousands to tens of thousands) for safety evaluations. Keep in mind that, to test effectiveness, you are looking for positive data. For side effects, you are looking for negative data. To find those minor but potentially serious side effects, you will need a large data set.

Also, a large data set is not always a good thing. I’m sure they have done a proper power analysis to justify their sample size (for testing effectiveness). It’s not always good to have large data set. Too many data points will give you false significance between placebo and test groups even if the differences are small and meaningless.

To be honest, I’m quite surprised by the amazing effectiveness. I’ll have to look at the actual data to see what’s going on. The key is their demographics table, typically their Table 1... How have they picked their samples...
 
Last edited:

taxiya

Brigadier
Registered Member
I think China's Fosun is also a parterre of Pfizer, as well as BioNTech, yet it was not even mentioned in the announcement.
Please, Log in or Register to view URLs content!
Is Fosun just a company supposed to be producing and distributing the Pfizer and BioNTech vaccines? It is not part of developing work besides organizing clinical trails. So I don't think such role deserve being mentioned. Think about the Chinese vaccines being trailed in other countries, the host countries institutes are not really mentioned much either if at all.
 

vesicles

Colonel
For effectiveness, you are testing significant differences between two data sets, placebo and test groups. For this type of comparison, you will need a sample size that should be carefully determined. A sample size too large will give you statistical significance even when the differences between two groups are very small. That's why you need a power analysis to determine the most proper data size. Power analysis will be one of the first things peer review will look at.

For safety, you are looking for a percentage of serious side effects within a single data set (including all those who get injections). No comparison involved. Then the larger the set the better. The harder you look, the more likely you will find those minor but serious side effects, and more confident you can be of the vaccines.
 
Top