Coronavirus 2019-2020 thread (no unsubstantiated rumours!)

taxiya

Brigadier
Registered Member
Please, Log in or Register to view URLs content!
What does the "protection against infection" mean by the bloomberg article? Is that even a scientific term in the study that bloomberg reported?

My understanding of vaccine is that they trigger the body to produce anti-bodies which hinder the virus' capability to replicate itself. So vaccine does not stop replication but only greatly reduce it. This means that there is always an infection, but only minimized by vaccine.

The wording "against infection" gives me the impression of TOTALLY prevent replication. That means that in the claimed percentage of chances people would have no virus replication in their body after the virus landed on their lung cell.

It sounds like among these protection chances every virus particle has an anti-body (or some chemical compound that body produced) waiting to kill the virus with 100% successful rate before the virus makes the first replication. I find this term hard to believe. It is like to say that infinite has a definite value. :oops:
 

OppositeDay

Senior Member
Registered Member
What does the "protection against infection" mean by the bloomberg article? Is that even a scientific term in the study that bloomberg reported?

My understanding of vaccine is that they trigger the body to produce anti-bodies which hinder the virus' capability to replicate itself. So vaccine does not stop replication but only greatly reduce it. This means that there is always an infection, but only minimized by vaccine.

The wording "against infection" gives me the impression of TOTALLY prevent replication. That means that in the claimed percentage of chances people would have no virus replication in their body after the virus landed on their lung cell.

It sounds like among these protection chances every virus particle has an anti-body (or some chemical compound that body produced) waiting to kill the virus with 100% successful rate before the virus makes the first replication. I find this term hard to believe. It is like to say that infinite has a definite value. :oops:

Probably defined operationally i.e. the subject is not infected just in case PCR testing gives a negative.
 

styx

Junior Member
Registered Member
The Winter Olympics is a drag on the use of national resources and given the current geopolitical climate, can't possibly enhance Chinese national image on the international stage like the 2008 Olympics did. However what is done is done. China must steel through this like the Japanese have this year.
but the new strain vaccine evading is possibly a gold occasion to cancel olympics and prepare for hard confrontation with usa.
 

badoc

Junior Member
Registered Member
GG
I can't see how humanity can fight something like this. Eventually we will have to accept that we must live with this
View attachment 79445
Inactivated virus uses the whole virus.
mRNA uses only the spike protein.
The new South African virus, Omicron, have a mutated spike protein.

Good Luck to those vaccinated with Pfizer and Moderna.

Please, Log in or Register to view URLs content!
The 50 mutations on the new B.1.1.529 variant, named Omicron by the World Health Organization, include more than 30 on the spike protein, the exposed part of the virus that binds with human cells.

Please, Log in or Register to view URLs content!
South African scientist Tulio de Oliveira said at a media briefing Thursday that the omicron variant contains around 50 mutations but more than 30 of these are in the spike protein, the region of the protein that interacts with human cells prior to cell entry.
.
 
Last edited:

Overbom

Brigadier
Registered Member
Inactivated virus uses the whole virus.
mRNA uses only the spike protein.
The new South African virus, Omicron, have a mutated spike protein.

Good Luck to those vaccinated with Pfizer and Moderna.
I am not well versed with vaccine technologies

Does the above mean that mRNA vaccines could potentially not work, or work with reduced effectiveness? And that also mean that inactivated virus vaccine is unaffected?

Would appreciate if someone could explain the consequences of this new variant to different vaccines technologies
 

gelgoog

Lieutenant General
Registered Member
Inactivated virus vaccines basically have the whole dead virus shell. So when you get vaccinated the whole virus shell is used in the immunization. The mRNA vaccines just replicate a small fraction of the virus shell, one of the spikes it uses to enter cells. This new variant supposedly has severe mutations mostly confined to that spike. You figure it out.
 
Top