solarz
Brigadier
It's about the availability of hosts to infect, not geographic spread to nearest population. All you done is shift the ceiling of how many target at-risk population you can infect from the tribal level to the world-wide level, but the natural selection pressure does not disappear because there is still a finite number of hosts to infect, whether at tribal or world-wide level. Therefore evolution still occur.
As sinophilia pointed out.... I never said lethal strains cannot happen. Mutations are random, so anything can happen, include more lethal variants. It's whether natural selective pressures annihilate maladaptive mutations or encourages it to flourish into a dominant strain. Hence the "tendency" or common average for it be more contagious and less lethal based on historical analysis of most viruses.
Evolution and natural selection still occurs because all you have done is shifted the limited available hosts to infect at the country or regional level (finite population: 300 Million) to another ecosystem with a limited available host to infect (world-wide finite population: 7.9 billion). It's not about geographical distance to nearest population, it's about the total available hosts (e.g. at-risk population) which is finite and limited on this earth, so evolution will still occur because these people will either gain immunity (natural or vaccine), or die off, thereby reducing the at-risk population.
Sure, so now that you've shifted the limited available hosts to the entire human population on Earth. The only way the pathogen is going to evolve into a less virulent strain is when all the virulent strains die out with their hosts. How much of the population will be culled this way? 10%? 20%? 50%? 90%? Nobody knows.
That's why all this talk of covid evolving to be less lethal is just wishful thinking. There is no data to support this view.