News on China's scientific and technological development.

Scientists from Nanjing University tailored a nanobody found in Alpaca to be 100% effective on HIV virus.


近日，南京大学医学院吴稚伟教授、吴喜林研究员助理教授课题组在这一领域取得了重要突破。基于课题组原创性的纳米抗体发现和工程改造平台，他们通过羊驼免疫和高通量噬菌体展示技术，成功从羊驼体内分离出一系列CD4纳米抗体。其中，Nb457在治疗HIV感染方面展现出巨大潜力，在检测的代表全球117株HIV假病毒里，只有一株病毒不能抑制，广谱性为99.1%，抗病毒活性为pM级，Nb457纳米抗体的广谱性和抗病毒活性明显优于现有的HIV中和抗体。

尤为引人注目的是，在HIV-1活病毒测试中，虽然Nb457和现有的CD4抗体药物（Iblizumab）都无法实现病毒的完全中和，但经过工程化改造的“乌纱帽”型三聚体纳米抗体Nb457-NbHSA-Nb457却实现了病毒的100%完全抑制。这一发现提示新型的“乌纱帽”型工程改造后的纳米抗体可以更好地抑制病毒感染，同时不易引发HIV的病毒耐药逃逸。

Xiaomi is not just a phone maker, but also makes all sort of consumer products and making them smart and connected

AMOLED and 8.6th gen production getting huge boost in China

tphuang said:

https://twitter.com/i/web/status/1838691675750764833

Xiaomi is not just a phone maker, but also makes all sort of consumer products and making them smart and connected

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For lower price electronics Xiaomi offers better value than Huawei or just about anyone else in China. Have used exercise bands from them and it was great.

tphuang said:

https://twitter.com/i/web/status/1838887728517112109

AMOLED and 8.6th gen production getting huge boost in China

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I wonder if the bad blood in relations have more to do with this than the geopolitical situation.

siegecrossbow said:

For lower price electronics Xiaomi offers better value than Huawei or just about anyone else in China. Have used exercise bands from them and it was great.



I wonder if the bad blood in relations have more to do with this than the geopolitical situation.

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Korea and China will not have a good geopolitical situation as long as China is de-industrializing Korea. What does Korea have left if Samsung, Hyundai and shipbuilding companies start making major cuts? 30% of some Samsung divisions will be cut. There is no saving this relationship

China is de-industrializing Korea partly because of geopolitics, though. If Korea can be a trusted component of the Chinese supply chain, then the two countries could simply agree to specialize in different areas of the supply chain, realizing comparative advantage and maintaining industry in both countries. But due to geopolitical risks and "de-coupling" forced by Korea's Western "allies," Korean suppliers simply cannot be relied upon.

It's not market forces alone that are driving China towards self-sufficiency. China's industrial strategy is intentional. Korea could have had a larger market share in China, if it weren't so bent on an adversarial relationship.

tphuang said:

Korea and China will not have a good geopolitical situation as long as China is de-industrializing Korea. What does Korea have left if Samsung, Hyundai and shipbuilding companies start making major cuts? 30% of some Samsung divisions will be cut. There is no saving this relationship

Click to expand...

Korea would be lucky to resist getting turned by US into Ukraine over Taiwan and lose all industry

Eventine said:

China is de-industrializing Korea partly because of geopolitics, though. If Korea can be a trusted component of the Chinese supply chain, then the two countries could simply agree to specialize in different areas of the supply chain, realizing comparative advantage and maintaining industry in both countries. But due to geopolitical risks and "de-coupling" forced by Korea's Western "allies," Korean suppliers simply cannot be relied upon.

It's not market forces alone that are driving China towards self-sufficiency. China's industrial strategy is intentional. Korea could have had a larger market share in China, if it weren't so bent on an adversarial relationship.

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That's nonsense.

China is de-industrializing Korea because its companies are beating Korean companies. Are you saying if Korea was friendly to China, China would not want its shipbuilding industry to beat Koreans? Or EVs? Or nuclear energy? Or semiconductor?

tphuang said:

That's nonsense.

China is de-industrializing Korea because its companies are beating Korean companies. Are you saying if Korea was friendly to China, China would not want its shipbuilding industry to beat Koreans? Or EVs? Or nuclear energy? Or semiconductor?

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If we ignore geopolitics and focus on just market forces, it's not about what China wants, it's about what makes sense for China to invest in and compete on, and what it makes sense for China to leave to others.

Opportunity costs dictate that you cannot be the best at everything. If Koreans are competent - and I think we can agree that they are - then there will inevitably be industries where they will have comparative advantage, simply because they'd be willing to specialize and commit more resources than would be warranted by opportunity costs from China's side. In those industries, it would not make economic sense for Chinese companies to even invest the resources to compete with them - as it DIDN'T make economic sense for Chinese companies to, for example, invest in developing high-end lithography machines until the US sanctions (hence the Chinese government having to subsidize it).

I'm not saying this is true specifically for shipbuilding, EV, nuclear energy, or semiconductors; but I want to get away from this idea that industrialization is a zero-sum game where China industrializing means others de-industrializing. That did not happen when the US industrialized and it did not happen when the EU re-industrialized, either.

tphuang said:

Korea and China will not have a good geopolitical situation as long as China is de-industrializing Korea. What does Korea have left if Samsung, Hyundai and shipbuilding companies start making major cuts? 30% of some Samsung divisions will be cut. There is no saving this relationship

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The conflict is not because of deindustrialization, it's simply just the Korean's brain damage. Korea should realize that for thousand of years, it is China's vassal state and should return to that status. If the Korean accept that, there will be no conflict, 天朝 will embrace you.