You need to see the replies to understand what I meant
News on China's scientific and technological development.
- Thread starter Quickie
- Start date
Patents are a great sign of China's technological progress, but practically, I don't think they are of any use if the West plays dirty & decides to "ignore Chinese patents," as they have done for Russia.
It has to be understood that the US is no longer interested in playing by global rules and that it is powerful enough to force most of the developed world to go with it, presuming it can manufacture a conflict - like by recognizing Taiwan's independence - to create the conditions for mass technology sanctions. These sanctions would necessarily include not recognizing Chinese patents.
In the wars to come between the West and China, all that will matter is having realized technologies and systems that do not depend on foreign imports. Since the US has shown that it is capable of strong arming anyone within its alliance system into doing what it wants, China should turn to countries outside of that system for cooperation in research & development. Countries in Southeast Asia, the Middle East, and Africa are especially promising.
It has to be understood that the US is no longer interested in playing by global rules and that it is powerful enough to force most of the developed world to go with it, presuming it can manufacture a conflict - like by recognizing Taiwan's independence - to create the conditions for mass technology sanctions. These sanctions would necessarily include not recognizing Chinese patents.
In the wars to come between the West and China, all that will matter is having realized technologies and systems that do not depend on foreign imports. Since the US has shown that it is capable of strong arming anyone within its alliance system into doing what it wants, China should turn to countries outside of that system for cooperation in research & development. Countries in Southeast Asia, the Middle East, and Africa are especially promising.
I agree, but the global South has low concentrations of STEM talent. It takes decades of patronage to establish a higher education oriented culture. Iran does but there are political issue with Open collaboration.
Realized technologies might also not be as important as the ability to manufacture and utilize technology. If the US has no ability to build 5G infrastructure, then the 5G patents from Huawei are useless to them. Meanwhile, there are plenty of interesting and useful patents China can appropriate from the West in a counter sanction, and benefit more comparatively. For example, seizing US biopharmaceutical IP, which enables big pharma racketeering, and allowing indigenous Chinese companies to manufacture exact duplicates would permanently end their industry and R&D capability overnight.
AssassinsMace
Lieutenant General
That's a two-way street. Remember after the US went after Huawei who held a lot of 5G patents, The US congress was talking about writing a law that allowed US telecoms to violate Chinese patents so they could advance US 5G technology without having to pay a license. How come it never got anywhere to pass? Because it's a slippery slope. The US violates Chinese patents... what's to stop China or any other country from stealing US patents? Who do you think has more to lose? That's why it never came to a vote in Congress. That tells you something because they already think China is stealing IP left and right, what's stopping them from doing the same to China? It's actually questionable if China is stealing IP and if it were happening it's not at a loss that would happen if it were open season to steal anyone's IP which would be the case if the US okayed the stealing of other countries' IP. The US and the West would be the big loser there.
I would like to see them try. Imagine if they can make EUV machines using ASML patents with no consequence lol
Indeed, being able to be a complete low cost replacement supplier that can scale quickly would be a true gamechanger in the international marketspace and greatly assist the Global South too.
That's why you need to make the biggest trade blocks so you can prevent the west ignoring your patents. Because if they start playing dirty with patents breaches you can prevent them from entering the trade block markets.
The value of patents is not in the paper itself but the technological know-how behind it. This is why the US is so scared.
Chinese researchers made breakthrough in treating Pakinson's disease with "genetically engineered mesenchymal stem cells".
Paper in English:
News in Chinese:
基因工程化间充质干细胞 为帕金森病治疗带来曙光
科技日报讯 （记者赵汉斌）帕金森病是继肿瘤、心脑血管疾病之后中老年健康的“第三杀手”。近日，科技日报记者从昆明理工大学灵长类转化医学研究院了解到，该院季维智院士、李天晴教授团队在应用基因工程化间充质干细胞治疗帕金森病方面取得重要进展。相关研究成果在线发表于国际期刊《自然伙伴期刊—帕金森病》。
目前，我国帕金森病患者已超300万人，年医疗费用超过2000亿元。这种疾病发病率和死亡率都非常高，6年内的死亡率高达66%。常规的临床治疗方法，长期使用会带来明显的副作用，后期还有失效之虞。因此开发安全、有效、经济并适合广大帕金森病患者的治疗方法，一直是整个医疗领域努力的方向。
李天晴、季维智团队耗时8年，潜心开发出用于帕金森病治疗的可持久稳定分泌多巴胺神经递质的基因工程化间充质干细胞，将其移植到大鼠和猴帕金森病模型后，可通过恢复纹状体多巴胺水平，实现中脑多巴胺环路的原位重建，并可快速恢复急性和慢性帕金森病猴模型的运动和非运动障碍缺陷。长达5年的结果评价，证明了该方法的安全性和有效性，显示出基因工程化间充质干细胞在未来帕金森病临床治疗应用中的巨大潜力。
此项研究有力地支持了基因工程化间充质干细胞移植在不同帕金森病模型中的显著治疗效果，其安全性可在移植前得以充分评估；同时可实现细胞的规模化和标准化扩增以及建立稳定的质控体系，用于细胞药物开发。此方法可以治疗包括重症在内的大部分帕金森病，且移植结果在2周内可发挥功效，有利于移植效果评价，减少临床费用。
Paper in English:
Abstract
Although striatal delivery of three critical genes for dopamine synthesis by viruses is a potential clinical approach for treating Parkinson’s disease (PD), the approach makes it difficult to finely control dopamine secretion amounts and brings safety concerns. Here, we generate genetically engineered mesenchymal stem cells encoding three critical genes for dopamine synthesis (DOPA-MSCs). DOPA-MSCs retain their MSC identity and stable ability to secrete dopamine during passaging. Following transplantation, DOPA-MSCs reinstate striatal dopamine levels and correct motor function in PD rats. Importantly, after grafting into the caudate and putamen, DOPA-MSCs provide homotopic reconstruction of midbrain dopamine pathways by restoring striatal dopamine levels, and safely and long-term (up to 51 months) correct motor disorders and nonmotor deficits in acute and chronic PD rhesus monkey models of PD even with advanced PD symptoms. The long-term benefits and safety results support the idea that the development of dopamine-synthesized engineered cell transplantation is an important strategy for treating PD.News in Chinese:
基因工程化间充质干细胞 为帕金森病治疗带来曙光
科技日报讯 （记者赵汉斌）帕金森病是继肿瘤、心脑血管疾病之后中老年健康的“第三杀手”。近日，科技日报记者从昆明理工大学灵长类转化医学研究院了解到，该院季维智院士、李天晴教授团队在应用基因工程化间充质干细胞治疗帕金森病方面取得重要进展。相关研究成果在线发表于国际期刊《自然伙伴期刊—帕金森病》。
目前，我国帕金森病患者已超300万人，年医疗费用超过2000亿元。这种疾病发病率和死亡率都非常高，6年内的死亡率高达66%。常规的临床治疗方法，长期使用会带来明显的副作用，后期还有失效之虞。因此开发安全、有效、经济并适合广大帕金森病患者的治疗方法，一直是整个医疗领域努力的方向。
李天晴、季维智团队耗时8年，潜心开发出用于帕金森病治疗的可持久稳定分泌多巴胺神经递质的基因工程化间充质干细胞，将其移植到大鼠和猴帕金森病模型后，可通过恢复纹状体多巴胺水平，实现中脑多巴胺环路的原位重建，并可快速恢复急性和慢性帕金森病猴模型的运动和非运动障碍缺陷。长达5年的结果评价，证明了该方法的安全性和有效性，显示出基因工程化间充质干细胞在未来帕金森病临床治疗应用中的巨大潜力。
此项研究有力地支持了基因工程化间充质干细胞移植在不同帕金森病模型中的显著治疗效果，其安全性可在移植前得以充分评估；同时可实现细胞的规模化和标准化扩增以及建立稳定的质控体系，用于细胞药物开发。此方法可以治疗包括重症在内的大部分帕金森病，且移植结果在2周内可发挥功效，有利于移植效果评价，减少临床费用。
I'd like to see a citation for this please, or at least some reference that I can read.
Patents are already public, that's how they get protection. From what I know, Huawei licenses 5G patents to United States anyway, because U.S. banned Huawei's 5G from United States and influenced EU to adopt a similar approach.