Coronavirus 2019-2020 thread (no unsubstantiated rumours!)

[supercat]

The results of the phase 1/2 trials of the Sinovac vaccine was published on the Lancet.

- After changing the production method, the effectiveness of the vaccine increased from 80%+ in phase 1 to 90%+ (it's actually as high as 98-99%, but Chinese researchers obviously have no intention to hype it up in such a scientific paper) in phase 2:

Notably, immune responses in phase 2 were much better than those recorded in phase 1, with seroconversion rates over 90% in both the 3 μg and 6 μg groups.

- As mentioned in previous reports, immunity can be induced quickly:

However, quick antibody responses could be induced within a relatively short time by using a day 0 and 14 vaccination schedule, which might be suitable for emergency use and is of vital importance during the COVID-19 pandemic.

- Although the level of antibodies induced by the vaccine is less than those in spontaneously recovered patients, it would not be a problem for 3 reasons:

However, we still think that CoronaVac could provide satisfying protection against COVID-19 on the basis of the following three reasons. First, from the experiences of other vaccines, such as the enterovirus 71 and varicella vaccines, most of the surrogate endpoints based on neutralising antibody titres have ranged from 8 to 24. Second, our preclinical study indicated that the neutralising antibody titres of 1/24 elicited in macaque models conferred complete protection against SARS-CoV-2. Third, although several studies have found that antibody responses generated from natural infection with coronaviruses (eg, SARS-CoV-2, severe acute respiratory syndrome coronavirus, and Middle East respiratory syndrome coronavirus) might decrease substantially over time, reinfection in these patients has rarely been reported, which indicates that immunological memory might have an important role of prevention of re-infections. Therefore, the antibody level itself might not be the key for a successful COVID-19 vaccine, but rather the establishment of a recallable specific immune response to SARS-CoV-2. Furthermore, the efficacy of the investigational vaccine and its surrogate endpoint need to be determined in a future phase 3 trial. Additionally, comparability of our serum antibody results with those of other COVID-19 vaccine studies is restricted.

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All these plus the fact that the vaccine can be stored in the refrigerate temperature of 2-8 degree Celsius for 3 years, I think China has got a potential winner at hand.

 

[localizer]

The results of the phase 1/2 trials of the Sinovac vaccine was published on the Lancet.

- After changing the production method, the effectiveness of the vaccine increased from 80%+ in phase 1 to 90%+ in phase 2:


- As mentioned in previous reports, immunity can be induced quickly:


- Although the level of antibodies induced by the vaccine is less than those in spontaneously recovered patients, it would not be a problem for 3 reasons:

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All these plus the fact that the vaccine can be stored in the refrigerate temperature of 2-8 degree Celsius for 3 years, I think China has got a potential winner at hand.

COVID everywhere but Western propaganda makes it hard for Chinese companies to gain trust for vaccine trials.

They want to make things worse for the rest of the world and blame it on Chinese.

 

[coolieno99]

Coronavirus hunters find new evidence pointing to the virus originating in Italy

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[KYli]

Chinese companies have already signed and secured many contracts with countries in Asia, ME, SA, and African. They are just waiting for the last hurdle to clear before the vaccination can begin. Chinese companies have been trying to enlist more countries to participate in the clinical trial to earn their trusts and future contracts. I think that most countries realize that they wouldn't get the vaccine from the West til at least the second and third batch of production. So China is their only choice as Russia is having problem to ramp up its production even for its own right now.

 

[hashtagpls]

Great way to visualise how many people have died and are continue to die in america today and the scale and volume of those deaths; as stalin once put it, one death is a tragedy, a million deaths is a statistic.

 

[AssassinsMace]

Coronavirus hunters find new evidence pointing to the virus originating in Italy

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All the countries that were willing to let their own people die to make a political point won't be admitting they were wrong if this were the case.

 

[discspinner]

All the countries that were willing to let their own people die to make a political point won't be admitting they were wrong if this were the case.

Here's my question. As Scott Gottlieb has constantly reminded us, the actual number of infections of COVID per day could be 4-5x higher than the actual number of new confirmed cases. If the US right now is having 0.5 - 1 million infections per day...in 6 months or 180 days, that's like 50% of the population. Herd immunity is reached at 65-70%. The vaccine would help, but not by much.

 

[Kaeshmiri]

Here's my question. As Scott Gottlieb has constantly reminded us, the actual number of infections of COVID per day could be 4-5x higher than the actual number of new confirmed cases. If the US right now is having 0.5 - 1 million infections per day...in 6 months or 180 days, that's like 50% of the population. Herd immunity is reached at 65-70%. The vaccine would help, but not by much.

The vaccine will help the stock market and that's the only thing America cares about.

 

[localizer]

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Chinese need to be careful, these people have no trouble throwing cannon fodder at us.

 

[emblem21]

Here's my question. As Scott Gottlieb has constantly reminded us, the actual number of infections of COVID per day could be 4-5x higher than the actual number of new confirmed cases. If the US right now is having 0.5 - 1 million infections per day...in 6 months or 180 days, that's like 50% of the population. Herd immunity is reached at 65-70%. The vaccine would help, but not by much.

Herd immunity may not work for this virus as people can continue to get infected and eventually die from this virus. This virus also continually mutates as shown in Denmark with the mink so unless the vaccine can target the very origin of this virus, any vaccine that doesn’t is a waste of time. Hence if the west chooses to pursue this path, I fear many millions will die for nothing and well with the lockdowns now going up, this is going to have some dire consequences as many people worry about the economy but can’t get there heads around the fact that while this virus may not be as lethal as past contagions, it is certainly much more infectious then any on prior and opening up economies without a sound plan simply lands people back at square one. The world should’ve worked together on this, but now it is simply far too late and believe the media is to blame for a lot of the misinformation going around