Coronavirus 2019-2020 thread (no unsubstantiated rumours!)

[ZeEa5KPul]

Then when poop hits the fan, the politicians simply tossed away the fact that the Chinese doctors and scientists have given them everything that they had and desperately tried to warn them of the danger since early January.

At least one of those politicians is paying a very heavy price for that nonchalance.

 

[Skye_ZTZ_113]

At least one of those politicians is paying a very heavy price for that nonchalance.

Yes I'm sure the 'Herd Immunity' is coming to (not figuratively) bite his ass. It is not with a triumphant sense of satisfaction that I view Johnson's current state (living in the UK and being told 2%+ of us would die???) , but there is a form of macabre justice at work here imho.

 

[ZeEa5KPul]

Yes I'm sure the 'Herd Immunity' is coming to (not figuratively) bite his ass. It is not with a triumphant sense of satisfaction that I view Johnson's current state (living in the UK and being told 2%+ of us would die???) , but there is a form of macabre justice at work here imho.

Well, his money has been put where his mouth is. If he makes it through, he can proudly claim he did his part for herd immunity.

 

[manqiangrexue]

The virus receptor gene is highly conserved and primal:

Ill assume these are potential hosts.

Homologs.

The ACE2 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, C.elegans, and frog.



300+ orthologs.

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The receptor gene might be conserved but how conserved is the precise binding site? Just like people, monkey, dolphins, dogs, cats, pigs, lizards and crickets all have heads but your girlfriend (the virus) only recognizes your head as the one to fall if you forget about your anniversary LOL Typically, that's how viruses work but this one might be more promiscuous; who knows?

This paper details the residues of the ACE receptor that are recognized by COVID-19 and the species' in which they most resemble those known to be recognizable by the virus (cat, dog, pangolin). It also includes a long list of animals that show incompatible residues with known viral recognition mechanism (S protein).

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[vesicles]

COVID-19 never ceases to amaze me. I have long stopped dismissing any figures or projections since I was shown wrong in dismissing @shanlung 's prediction that it would become a pandemic. I'm all just watch and see now.

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A tiger at the Bronx Zoo tests positive for coronavirus

(CNN)Nadia, a tiger at the Bronx Zoo in New York, has become the first of her kind to test positive for the

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.
The 4-year-old female Malayan tiger tested positive after developing a dry cough and is expected to recover, the Wildlife Conservation Society's Bronx Zoo said in a

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.

Samples from Nadia were taken and tested after the tiger -- and five other tigers and lions at the zoo -- began showing symptoms of respiratory illness, according to the

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(USDA). No other animals at the zoo are showing symptoms.

To the best of my knowledge, the big cats like tigers and lions are the first ones that actually respond to the COVID-19. This is very interesting. While the virus has been found on other pets like dogs and house cats, none of the animals has shown symptoms. This means, to the virus, these pets are simply surfaces to land on, like tables and elevator buttons.

However, tigers are different. They show symptoms, which means the virus is actively replicating and inflicting immune responses from the tigers. This mean the virus has successfully jumped from human to tiger. And the tiger is an actual host of the virus. With such a short period of time and such limited contact between a single zoo keeper and 6-7 big cats, it's almost impossible for the virus to mutate enough to fit the conditions in tigers and lions immediately after jumping from a human. And the tigers are showing the same symptoms as human, i.e. dry coughs, etc. That means that virus has not mutated since jumped from the zoo keeper to the tigers.

This could suggest one thing: the virus might have existed in tigers before! And it's very possible that the virus might have initially jumped from tigers to human! so tigers might be the missing linking between bats and human... At some time in the near past, this virus, which has existed in tigers for some time, jumped on human and mutated enough to make human its new host. And in the case of the NYC zoo, the virus simply jumped back to its original host, a tiger... Just a guess...

There is a large Bengal tiger population in the central China and the Chinese hunt tigers for their bones for Chinese medicine...

 

[solarz]

Virus infection is usually very specific to certain animals. Hopefully, the corona virus doesn't go further than infecting cats, the tiger included.

Could this be a clue to the origin of the virus? Could it have come from some species of cat?

 

[Anlsvrthng]

Looks like New York is the earth most infected area at the moment.

599 death / day in a 10 million area, it is very high , I think unprecedented .

And it is still in early phase.

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Well, his money has been put where his mouth is. If he makes it through, he can proudly claim he did his part for herd immunity.

Any other plan ?

I mean, no one can live forever in lockdown .

 

[solarz]

There is a large Bengal tiger population in the central China and the Chinese hunt tigers for their bones for Chinese medicine...

I don't think anyone has been hunting tigers in China for a very long time.

 

[vesicles]

I don't think anyone has been hunting tigers in China for a very long time.

Poaching, actually... You still see tiger bones in Chinese medicine...

 

[manqiangrexue]

To the best of my knowledge, the big cats like tigers and lions are the first ones that actually respond to the COVID-19. This is very interesting. While the virus has been found on other pets like dogs and house cats, none of the animals has shown symptoms. This means, to the virus, these pets are simply surfaces to land on, like tables and elevator buttons.

However, tigers are different. They show symptoms, which means the virus is actively replicating and inflicting immune responses from the tigers. This mean the virus has successfully jumped from human to tiger. And the tiger is an actual host of the virus. With such a short period of time and such limited contact between a single zoo keeper and 6-7 big cats, it's almost impossible for the virus to mutate enough to fit the conditions in tigers and lions immediately after jumping from a human. And the tigers are showing the same symptoms as human, i.e. dry coughs, etc. That means that virus has not mutated since jumped from the zoo keeper to the tigers.

This could suggest one thing: the virus might have existed in tigers before! And it's very possible that the virus might have initially jumped from tigers to human! so tigers might be the missing linking between bats and human... At some time in the near past, this virus, which has existed in tigers for some time, jumped on human and mutated enough to make human its new host. And in the case of the NYC zoo, the virus simply jumped back to its original host, a tiger... Just a guess...

There is a large Bengal tiger population in the central China and the Chinese hunt tigers for their bones for Chinese medicine...

I don't think so at all.

If tigers were the intermediate host before man, then there should have been outbreaks in zoos among zoo keepers. If this disease had existed in tigers for a long time, they would have infected their keepers long before this year. Tigers haven't been hunted in China for decades.

The paper I posted analyzed the susceptibility of 5 critical residues on the ACE receptors to the S protein of SARS-CoV-2 and found feline, canine, and pangolin to be susceptible via in silica modelling. So while these animals may show no symptoms, they can be vectors, making them immune while still allowing viral replication and transmission.

The virus may not need to mutate at all to infect tigers if cats were a vector beforehand.

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