Well, we started "flying", operating Blackbirds, SR-71's and MC-130E's in the early to mid 60s, those two aircraft were benchmarks, and both of those aircraft performed far beyond expectations. My own Dad flew the MC-130E from the fall of 67-through the fall of 68. His office was in the US Embassy in Saigon working for MACVSOG, he had between 65 to 70 hours of combat time in that aircraft, in country.
Back to Mr Weiss's point, the F-22 was a fully integrated operating system, and wildly successful beyond our wildest imaginings in spite of several significant design issues that had to be addressed, and even today make this a very high maintenance bird in order to maintain her capabilities.
Back on Topic, the F-35 is the most synergistic fighting system ever designed, and is really in the "toddler stage of development". It will "learn" as it grows up, and each successive upgrade will bring it more and more capability, indeed it is also very adaptive--(plug and play) weapons systems, etc.
In the world of 5th gen fighters, the phrase "you have to crawl before you can walk" are absolutely true. There have never been any "shortcuts" in 5th Gen, and it is very, very, very costly in time invested, as well as money, you can't "through money at it", and expect to get to the top, that comes one rung at a time!