Coronavirus 2019-2020 thread (no unsubstantiated rumours!)
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What this study shows is that two doses of mRNA vaccines are indeed better than traditional vaccines. Ever since the beginning of administration of covid vaccines, these mRNA vaccines have prevented more serious infections earlier on, instead of having to wait for a few additional months for the third dose to take the full effect.
That's because Pfizer is 30 micrograms per dose and Moderna is 100 micrograms per dose and Sinovac is 3 micrograms per dose. The difference in the shots’ performance can be summed up with more is better.
That's why when Pfizer trial for under 5 years old with 3 micrograms and 10 micrograms failed to generate enough antibodies. However, when using 30 micrograms for kids under 5 years old, they would get high fever. In the contrary, Sinovac doesn't have the same problem and its vaccine is safe for kids under 5. That's why HK government waited for months and never received Pfizer study results and was forced to use only Sinovac.
If Pfizer causes fever, that would mean it is very effective. For the appropriate dosage, it is always a balance between effectiveness and side effects.
Do you know what high fever mean for kids? High fever for kids can be deadly. That's why Pfizer is forced to test 3 doses for kids because high fever is not acceptable for kids.
48 percent for Pfizer vs 64.6 percent for Sinovac for preventing hospitalizations. Sinovac's performance in kids is much better than Pfizer after Pfizer gives kids with 10 micrograms. As for 3 micrograms Pfizer vaccine is basically useless.
The vaccine’s effectiveness against hospitalization declined to 73 percent from 85 percent in the older children. In the younger children, effectiveness dropped to 48 percent from 100 percent. But because few children were hospitalized, these estimates have wide margins of error.
The numbers for protection from infection are more reliable. Vaccine effectiveness against infection in the older children decreased to 51 percent from 66 percent. But in the younger children, it dropped sharply to just 12 percent from 68 percent.
The submission was surprising because in December the companies said early trial results of the two low doses of the vaccine fell short of expectations, and it amended its clinical trial to test a three-dose version.
China-based Sinovac Biotech Ltd's COVID-19 vaccine was 38.2% effective in preventing infections during the Omicron wave in children aged three to five years, a study in Chile showed.
The findings are in contrast to earlier studies that showed the vaccine, CoronaVac, was 74.5% effective in preventing infections in children aged 6 to 16 years, when Delta was the dominant variant.
Countries are increasingly recommending booster doses in the face of the circulating Omicron variant, which the World Health Organization has said can bypass some protection imparted by vaccines. Most vaccines are still effective against severe infections.
Sinovac's vaccine was 64.6% effective in preventing hospitalizations and 69% effective in preventing COVID-19 related ICU admissions, the Chilean study also showed.
If the scale of this problem is massive, then this will be a boon for China, as countries heavily affected by Covid will need to shift their financial resources into taking care of the disabled. Those countries being the ones that are hostile against China. Though I feel bad for the common folks that got affected.
Meh. I don't. These are the same people itching to see China's zero Covid fail so millions of Chinese die. Not happening. Alternatively, let's see how your economy deals with almost everyone being infected and reinfected with Covid.
I'm also sick of seeing those comments and articles joyfully cheering that China's covid cases reached new high (despite it being lower than any major countries). I just feel bad for those that got affected, because I lost one of my uncle to covid.
The reason why they aren't yet is because everybody has already been infected with delta and re-infected with the original Omicron strain. They have a lot of natural immunity to BA.2 variant.