If the ship is using its increased size for say, better liveability for the crew on long journeys, more stores, more cooling equipment for the radar, more electronics and computing back end, and for some other things, yes, a ship would sacrifice VLS for other things. After all, the Zumwalt despite its displacement, only has 70 VLS. If you look at the upcoming German MKS 180 surface combatant, that would displace 10,000 or even 11,000 tons, yet it only has 64 VLS and half of them will use ESSM, not in quads, but in singles.