Coronavirus 2019-2020 thread (no unsubstantiated rumours!)
- Thread starter localizer
- Start date
where have you been?
The Philippines manufacturing partner for Livzon's V-01 vaccine candidate announced enough data has been collected for an interim analysis, which will be finished by the end of the month. Depending on the results they will apply for an EUA. The phase III trial is being conducted in the Philippines, Indonesia and Russia.
A separate Phase III trial for V-01 as booster is ongoing in Pakistan and Indonesia.
Very lucky they're getting results before Omicron has the time to tank the numbers.
The Philippines recently approved Phase III human trials for Recbio Technology's ReCOV, a protein vaccine candidate adjuvated with Recbio's own BFA03 adjuvant (similar to GSK's AS03). People may remember ReCOV from SCMP's reporting last year
ReCOV's immunogenicity is stronger than BNT-Pfizer and comparable to Moderna, and stays consistent across multiple variants. From published data it's strong against the beta variant (a good predicator for Omicron) and delta. Recbio says it's also strong against Omicron.
Recbio is also applying for Phase I human trials for its lyophilized mRNA vaccine candidate which can be stored at room temperature.
In separate news, apparently Walvax has collected enough data (i.e. enough infections) from Phase III trials for its mRNA vaccine candidate, so expect results in a few weeks.
Coughing is usually required to aerolizes viral particles to micrometer form or individual viral particles.
Just talking or breathing creates large droplets of viruses which are large enough to be filterable by masks.
And that's why masks work so well since most people with symptoms are just talking or breathing, producing large droplets and not coughing the micrometer forms of the virus particles.
Nobody said coughing is the only way to transmit. Stop putting words and attacking a strawman. Generally, coughing is generally required to aerolize virus into micrometer form. Dippy.
Yet again, stop attacking a strawman. Coughing is required to aerolizes virus into micrometer form. Just talking and breathing generally produces large droplets that are filterable by masks. That's why masks work.
Viral load matters. Masks reduces exposure to high viral load which can reduce symptom severity and reduces time to onset of symptoms which reduces contagiousness. You forgot the benefits by focusing solely on virus size.
This has nothing to do with virus size, stop changing the topic. Idiot anti-masker.
Source: I took Airborne Particles course for grad school.
From Nury Vittachi
I will post some of the difference between KN95 and N95 again for the benefit of forum readers. I have posted many times on this.
KN95 and N95 are not totally equivalent.
Most of the KN95 seen outside of China are "civilian grade", they use earloops like the regular surgical masks. If you pay attention to the photos of healthcare workers in China, they are usually wearing the "medical grade" which has head straps. The earloops are much easier to put on and take off, which makes it more ideal for day to day use. The filtering "mask" is essentially the same though, basically a hybrid.
I am not totally sure any manufacturers shut down as @KYli mentioned, but generally his statement matches my observation. I did not hear of many new domestic manufacturing lines of N95 popping up (surgical masks, are a different story, there are many new ones, probably equipment sold at a discount from China), suggesting the current capacity is enough.
What happened early on was a lot of misinformation, fabrications, profiteers, and confusion. Since there is no Western equivalent to "civilian grade" KN95, many of these were considered "not to N95 standard". This is fair, because even in China, they are not up to the medical standard. However, the news early on never made that entirely clear (Or even if they ever really knew). Obviously with this situation, there is going to be dishonesty and confusion on both ends. To the credit of the Chinese government, they tried very hard to crackdown on their end to protect the national reputation.
Actually the civilian KN95's continued importation into America is owing to the fact that it is considered a superior product compared to a regular disposable mask. Cost was mentioned, well KN95 cost is still more than an average earloop mask. It better established that it is not the same as N95, nor is it still being misrepresented like that. I think it helped that the NBA and NFL adopted them.
It is also now being produced in black colour often so it is not confused with a medical grade mask (since early on people were being hassled for "stealing" masks from healthcare workers due to the shortage)
Just wanted to add, actually now you see quite a few POSITIVE articles on KN95.
KN95 and N95 are not totally equivalent.
You see the yellow straps going around the back of the mask in this picture. This is a requirement for N95 standard. Because it goes around the back of the head when you wear it, the seal is much better. However, this also makes it more uncomfortable.
Most of the KN95 seen outside of China are "civilian grade", they use earloops like the regular surgical masks. If you pay attention to the photos of healthcare workers in China, they are usually wearing the "medical grade" which has head straps. The earloops are much easier to put on and take off, which makes it more ideal for day to day use. The filtering "mask" is essentially the same though, basically a hybrid.
I am not totally sure any manufacturers shut down as @KYli mentioned, but generally his statement matches my observation. I did not hear of many new domestic manufacturing lines of N95 popping up (surgical masks, are a different story, there are many new ones, probably equipment sold at a discount from China), suggesting the current capacity is enough.
What happened early on was a lot of misinformation, fabrications, profiteers, and confusion. Since there is no Western equivalent to "civilian grade" KN95, many of these were considered "not to N95 standard". This is fair, because even in China, they are not up to the medical standard. However, the news early on never made that entirely clear (Or even if they ever really knew). Obviously with this situation, there is going to be dishonesty and confusion on both ends. To the credit of the Chinese government, they tried very hard to crackdown on their end to protect the national reputation.
Actually the civilian KN95's continued importation into America is owing to the fact that it is considered a superior product compared to a regular disposable mask. Cost was mentioned, well KN95 cost is still more than an average earloop mask. It better established that it is not the same as N95, nor is it still being misrepresented like that. I think it helped that the NBA and NFL adopted them.
It is also now being produced in black colour often so it is not confused with a medical grade mask (since early on people were being hassled for "stealing" masks from healthcare workers due to the shortage)
Just wanted to add, actually now you see quite a few POSITIVE articles on KN95.
The fact that US hospitals are getting overwhelmed just proves that they strategy is even worst than Chinese 'zero-COVID' strategy. If the US hospital system can't take the influx of patients from your "minor cold/flu", then your COVID strategy is a failure. Atleast with the Chinese strategy, hospitals are not overwhelmed and cases are extremely low. With the US strategy, you have overwhelmed hospitals, high cases, and high deaths. What exactly are you achieving with the 'zero-Action' strategy?
"'Zero-action' strategy" says it all.