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Mast cell is responsible for triggering fast and strong allergic reactions. Chinese researches are trying to use this reaction to fight cancer.
Chinese scientists use allergy-like immune response for cancer therapy
Instead of allowing mast cells to respond to allergens, the team reprogrammed them using IgE antibodies that recognize proteins found on tumor cells.
When these customized mast cells are injected into the bloodstream, they travel to tumors and unleash sudden bursts of inflammation upon encountering their specific cancer target.
Sensitized mast cells for targeted drug delivery and augmented cancer immunotherapy