The late Ayatollah was vehemently against nukes for religious reasons, given his stature as a pope like figure in Shia Islam, this was expected and so his assassination by Israel and America is not just ill advised but reflects a desire to destroy Iran as a state and civilisational entity.
israel and the U.S. government through a system where they keep targeting and assassinating leaders until someone cowardly and feckless like Pezeshkian comes to power and negotiates terms favourable for Israel but it appears even the cowardice of Pezeshkian did not please the Israelis.